基因编辑降脂新突破、膳食补充剂真相、热咖啡健康警告与117岁长寿细胞奥秘

本期节目为您带来前沿健康与医学资讯:科学家研发出一次性注射可降低50%坏胆固醇的基因编辑纳米药;专家质疑膳食补充剂的实际功效,并警告其可能损害大脑健康;研究表明饮用过热饮品会使食道癌风险增加三倍,而快步走比一万步目标更益于长寿;此外,猪肾移植和深层睡眠排毒研究取得新进展,117岁西班牙老人的细胞更是揭示了减缓衰老的秘密。

By Grace & Ethan10 min listen10 min read
The preface image of article HEALTH-2026.09.12
The preface image of article HEALTH-2026.09.12

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Interactive transcript · 191 lines

Good morning, everyone.

早上好,大家。

Welcome to TalkCast, your trusted daily dose of fresh global news and easy -to -follow English learning.

欢迎收听 TalkCast,这里是您每日值得信赖的新鲜全球新闻与轻松易学的英语学习内容。

I am Grace.

我是 Grace。

And a very beautiful morning to you all.

祝大家度过一个非常美好的早晨。

I am Ethan.

我是 Ethan。

Today is September 12, 2026, and we are absolutely thrilled to have you starting your day with us.

今天是2026年9月12日,能与您一起开启新的一天,我们感到无比激动。

Before we jump into today's fascinating headlines, we want to share some love.

在切入今天吸引人的头条新闻之前,我们想表达一些感谢。

A massive thank you to all our wonderful TalkCast members.

向我们所有优秀的 TalkCast 会员表示巨大的感谢。

Your support keeps this show running, allowing us to produce high -quality daily episodes for English

您的支持维持着频道的运转,让我们能制作高质量的每日单集供英语

learners worldwide.

全球学习者收听。

Yes, we are incredibly grateful.

是的,我们无比感激。

If you enjoy our show and want to help us grow, please consider joining our TalkCast membership.

如果您喜欢我们的节目并希望帮助我们成长,请考虑加入我们的 TalkCast 会员。

We truly need and appreciate your support to keep bringing you this daily digest.

我们真心需要并非常感谢您的支持,以继续为您带来这份每日文摘。

Now let us preview today's exciting lineup.

现在让我们来预览今天令人兴奋的内容阵容。

We start with a major medical headline, a groundbreaking DNA gene editing treatment that can cut bad

我们首先来看一条重磅医疗头条,一种开创性的 DNA 基因编辑疗法,它可以大幅降低坏

cholesterol in half with just a single shot.

仅需一针即可将胆固醇降低一半。

Then, we will take a hard look at dietary supplements.

然后,我们将深入探讨饮食补充剂。

Why do experts doubt their benefits, and could they actually harm an aging brain?

为什么专家对其功效持怀疑态度,它们真的会伤害衰老的大脑吗?

Plus, we've got some hot news about how your morning coffee temperature might affect your cancer

此外,我们还带来了一则热点新闻,关于早晨饮用咖啡的温度可能会如何影响你的癌症

risk, and why your walking speed is way more important than hitting 10 ,000 steps.

风险,以及为什么你的步行速度远比走完一万步更重要。

We'll also check out our record -breaking transplant success involving a pig kidney, and finally,

我们还将关注一项涉及猪肾的破纪录移植成功案例,最后,

look at the curious case of a 117 -year -old woman whose cells seem to possess a magical mix of age

看看一位117岁老人奇特的案例,她的细胞似乎融合了衰老

and youth.

与青春的神奇特征。

That is an amazing lineup.

这真是令人惊叹的阵容。

Let's dive right into the details.

让我们直接深入了解细节。

Let us start with our top story today.

让我们从今天的头条新闻开始。

Scientists have developed a revolutionary DNA treatment that can reduce bad cholesterol by nearly 50

科学家们研发出一种革命性的 DNA 疗法,可以将坏胆固醇降低近50

% without the need for daily pills like statins.

%,而无需像以前那样每天服用他汀类药物。

Wait, Grace, did you say a DNA treatment and 50 %?

等等,Grace,你是说 DNA 疗法和 50% 吗?

That sounds like something out of a sci -fi movie.

听起来像是科幻电影里的情节。

What exactly is bad cholesterol, and why do we want to get rid of it?

坏胆固醇到底是什么?为什么我们要消除它?

In medical terms, it's called LDL cholesterol, which stands for low -density lipoprotein.

在医学术语中,它被称为低密度脂蛋白胆固醇(LDL)。

Doctors call it bad cholesterol because if you have too much of it, it builds up in your blood

医生称之为坏胆固醇,因为如果积累过多,它就会在血液中堆积

vessels, forming hard plaques.

血管中,形成坚硬的斑块。

Over time, these plaques clog your arteries, which can lead to serious heart attacks or strokes.

久而久之,这些斑块会堵塞你的动脉,从而引发严重的心脏病发作或中风。

Ah, okay.

啊,好吧。

So it's like grease building up inside the plumbing of a house.

所以这就像油脂堆积在房屋的水管内部一样。

But how does a DNA treatment fix this?

但是 DNA 疗法是如何解决这个问题的呢?

Are they changing our genetics permanently?

他们是在永久改变我们的基因吗?

In a way, yes, but only in a highly targeted, safe way.

在某种程度上是的,但仅以高度精准的、安全的方式进行。

This is a gene -editing nanodrug.

这是一种基因编辑纳米药物。

It goes straight to the liver and permanently turns off a specific gene that tells your body to make

它直接进入肝脏,并永久关闭一个指令身体制造

so much bad cholesterol.

如此多坏胆固醇的特定基因。

Whoa, gene -editing nanodrug.

哇,基因编辑纳米药物。

That is a very complex term.

那真是个非常复杂的术语。

Can you break that down into a simple picture for our listeners?

你能为我们的听众把它打比方说明白吗?

Of course.

那是当然。

Let's use a metaphor.

让我们用一个比喻。

Think of your DNA as a giant master cookbook for your body.

把你的 DNA 想象成一本巨大的身体总食谱。

The gene that makes bad cholesterol is like a bad recipe in that book that causes your kitchen to

产生坏胆固醇的基因就像那本书里的一道糟糕菜谱,导致你的厨房

produce a heavy, greasy sauce that clogs the pipes.

产生黏稠重油的酱汁,从而堵塞管道。

This new treatment acts like a tiny, smart white -out pen.

这种全新的疗法就像一支精巧智能的修正笔。

It goes into the cookbook, finds that specific bad recipe, and permanently crosses it out.

它进入食谱,找到那个特定的坏配方,并永久地将其划掉。

The kitchen is still perfectly fine, but it just stops making that greasy sauce forever.

厨房依然完好无损,但它不再制造那种油腻的酱汁了。

That is brilliant.

那真是绝妙。

A smart white -out pen for a bad recipe.

针对坏食谱的智能修正笔。

So instead of taking a daily pill to clean up the greasy sauce, you just cross out the recipe so it

因此,你不必每天吃药片来清理油腻的酱汁,而是直接划掉食谱,这样它

never gets made in the first place.

就绝不会从一开始被制作出来。

Exactly, Ethan.

一点没错,伊森。

And because it's a single shot, patients do not have to worry about forgetting their daily medication.

因为这是一针搞定,患者不必担心忘记每天服药物。

It's a massive breakthrough for heart health.

这是心脏健康领域的重大突破。

That is incredibly promising.

这听起来非常有前景。

But speaking of taking things daily, let's move to our second story.

不过说到日常的服药习惯,让我们转入第二个报道。

It seems about 80 % of Americans love taking dietary supplements, like vitamins and minerals.

似乎约有80%的美国人喜欢服用膳食补充剂,如维生素和矿物质。

But doctors are starting to raise a serious warning about this habit.

但是医生们开始对这种习惯提出严厉的警告。

Yes, indeed.

是的,确实如此。

A new survey shows that while the supplement industry is worth billions of dollars, medical experts

一项最新的调查显示,虽然补充剂行业价值数十亿美元,但医学专家

are highly skeptical about whether these pills actually do any good.

对这些药片是否真的有益持高度怀疑的态度。

Even more concerning, scientists are starting to worry that popular supplements could actually harm

更令人担忧的是,科学家们开始担心大众欢迎的补充剂实际上可能会损害

an aging brain.

衰老的大脑。

Wait, really?

等等,真的吗?

I take a multivitamin and some fish oil every morning because I thought I was helping my body stay healthy.

我每天早上都吃复合维生素和鱼油,因为我以为这能帮助身体保持健康。

Now you're saying they might be useless or worse, dangerous?

现在你却说它们可能是无用的,甚至更糟,是有害的?

For most healthy people, yes, they might be unnecessary.

对于大多数健康人群来说,是的,它们可能是不必要的。

Our bodies are designed to absorb nutrients best from real food, like fresh fruits, vegetables, and

我们的身体天然最擅长从天然食物中吸收营养成分,比如新鲜水果、蔬菜以及

whole grains.

全谷物。

When we take highly concentrated vitamins in pill form, our bodies often cannot process them properly.

当我们以药片形式摄入高浓度的维生素时,我们的身体往往无法妥善处理它们。

Can you give us an easy analogy to explain why taking too many supplements can be bad?

你能举个简单的类比来解释为什么吃太多补充剂不好吗?

Think of your body like a car.

想象你的身体就像一辆汽车。

If you fill your car with regular, high -quality gasoline and keep it well -maintained, it runs perfectly.

如果你给汽车加普通的优质汽油,并且保持良好的保养,它就能完美运行。

Taking too many dietary supplements is like dumping extra premium fuel, engine boosters, and

摄入过多的膳食补充剂就像是一股脑倾倒额外的优质燃料、发动机助推剂和

specialized oils into the tank all at once.

专用的机油一次性全部倒入油箱。

Not only is it a waste of money, but all those unnecessary fluids can actually clog the car's

这不仅浪费钱,而且所有这些不必要的液体实际上还会堵塞汽车的

filters and damage the delicate engine parts over time. Wow.

滤清器,久而久之会损坏精密的发动机零部件。哇。

So more is not always better.

所以多并不总是更好。

The extra supplements are just clogging up my engine.

多余的补充剂只会堵塞我的发动机。

And what about the brain connection?

那与大脑的关联又是怎么回事呢?

Scientists are concerned that excessive amounts of certain minerals and vitamins can build up in the

科学家们担心,过量的某些矿物质和维生素会在

brain over decades, causing chemical stress that can actually accelerate brain aging instead of

大脑中留存数十年,造成化学压力,实际上可能会加速大脑衰老,而不是

protecting it.

保护它。

So the best advice is to get your nutrients from a balanced diet and only take supplements if a

因此,最好的建议是从均衡的饮食中获取营养,只有当

doctor specifically prescribes them for a deficiency.

医生针对某种缺乏症明确开具处方时才服用补充剂。

That is a great reality check.

这真是一个极好的现实提醒。

I might need to save some money and put down the vitamin bottle.

我可能需要省点钱,把维生素瓶子放下了。

Speaking of morning routines, many of our listeners probably have a hot cup of coffee or tea next to

说到早晨的日常习惯,我们许多听众现在旁边可能正放着一杯热咖啡或热茶

them right now.

就在此刻。

But a massive new study has a very warm warning for us.

但一项大规模的最新研究对我们提出了温热的警告。

Indeed, Ethan.

确实如此,伊森。

A study involving nearly one million adults has linked drinking very hot beverages to a tripled risk

一项涉及近一百万成年人的研究将饮用极烫的饮品与风险增加两倍联系了起来

of esophageal cancer.

患食道癌的风险。

Tripled risk?

风险翻了三倍?

That is a scary statistic.

那是一个让人害怕的统计数据。

But how hot is very hot?

但是多热才算非常热呢?

Do I need to let my morning coffee go completely cold?

我需要让我早上的咖啡完全变凉吗?

No, you do not need to drink iced coffee every day.

不,你不需要每天都喝冰咖啡。

The risk applies to drinks hotter than 65 degrees Celsius, which is about 149 degrees Fahrenheit.

该风险适用于高于65摄氏度的饮料,大约相当于149华氏度。

At that temperature, the hot liquid physically burns the delicate lining of your esophagus, which is

在那个温度下,热液体会灼伤你食道娇嫩的内壁,而食道是

the food pipe connecting your mouth to your stomach.

连接你的嘴巴和胃部的食物通道。

Ah, the food pipe.

啊,食物管道。

So if we constantly burn that pipe, the cells have to keep repairing themselves.

所以如果我们不断地烫伤那个管道,细胞就必须不断进行自我修复。

And that constant rapid cell repair increases the chance of a genetic mistake, which can lead to cancer. Exactly.

而这种持续快速的细胞修复增加了基因出错的概率,从而可能导致癌症。一点也没错。

It is like scraping your knee on the pavement every single day.

这就像每天都在人行道上擦伤膝盖一样。

Eventually, the skin gets damaged and scarred.

最终,皮肤会受损并留下疤痕。

So the simple fix is to just wait a few minutes for your drink to cool down before taking a sip.

所以简单的解决办法就是,在啜饮之前,先等几分钟让饮料放凉。

A very easy fix indeed.

确实是一个非常简单的解决办法。

Just let it cool.

只需让它放凉即可。

And while we wait for a quick walk, a new study shows we might not need to hit that famous 10 ,000

在我们等待去散散步时,一项新研究表明我们可能不需要达到那著名的10,000

steps goal to get amazing health benefits.

步的目标就能获得令人惊叹的健康益处。

That is right.

一点没错。

Researchers found that walking briskly, meaning walking fast with energy, is actually far more

研究人员发现,轻快地行走(意思是快速且充满活力地行走)实际上远比

important for lowering your risk of death than just hitting a high step count.

对于降低死亡风险而言,比单纯追求高步数重要得多。

Even adding just an extra 1 ,000 steps a day at a faster pace can significantly protect your heart.

即使每天以更快的步伐多走1000步,也能显著保护你的心脏。

So it's quality over quantity.

所以质量胜于数量。

Walking fast is like revving your body's engine to clear out the dust.

快走就像提速你身体的引擎来清除灰尘。

Rather than just letting it roll slowly downhill for miles, it wakes up your entire system much better. Exactly.

而不是让它慢吞吞地沿着下坡滚动数英里,这能更好地唤醒你整个系统。一点也没错。

Speed matters.

速度很重要。

Now let's move on to our quick news briefs.

现在让我们来看看我们的新闻简讯。

First up, and an extraordinary medical milestone, a genetically modified pig kidney has successfully

首先,这是一项非凡的医疗里程碑,一个基因改造的猪肾脏已经成功

kept a human patient alive for a record nine months.

让一名人类患者维持生命长达创纪录的九个月。

This breakthrough buys crucial time for patients waiting for a human donor organ to become available.

这一突破为等待人类捐献器官的患者赢得了宝贵的时间。

Nine months?

九个月?

That is incredible.

那真是难以置信。

Using a pig organ is like using a temporary spare tire on your car.

使用猪的器官就像在你的车上使用临时的备胎。

It's not meant to be there forever, but it keeps the car moving safely down the road until you can

它并不打算永远装在那里,但它能让汽车安全地继续行驶,直到你能

get to the shop and buy a proper permanent human organ.

去维修店购买一个合适且永久的人体器官。

That is a perfect analogy, Ethan.

这是一个非常完美的类比,伊森。

Our second brief is a warning about sleep.

我们的第二条简讯是关于睡眠的警告。

A new study has linked deep sleep loss to the buildup of a toxic protein associated with Alzheimer's disease.

一项新研究将深度睡眠缺失与阿尔茨海默病相关的有毒蛋白积聚联系起来。

Scientists found that deep sleep acts like a brainwashing cycle.

科学家发现,深度睡眠就像是一个大脑清洗循环。

A brainwashing cycle?

大脑清洗循环?

That sounds a bit intense, but it makes sense.

听起来有点剧烈,但确实有道理。

During deep sleep, our brain cells shrink slightly, allowing spinal fluid to rush through and wash

在深度睡眠期间,我们的脑细胞会轻微收缩,允许脑脊液冲刷过去并清洗

away all the metabolic waste, including those toxic proteins.

掉所有的新陈代谢废物,包括那些有毒蛋白。

If we skip deep sleep, the trash just piles up.

如果我们跳过深度睡眠,垃圾就会堆积起来。

Spot on.

完全正确。

We have to make sure we protect our deep sleep.

我们必须确保保护好我们的深度睡眠。

Finally, let's look at some highly inspiring news about longevity.

最后,让我们来看看一些关于长寿的极具启发性的新闻。

Scientists have studied the cells of a 117 -year -old Spanish woman and found something truly remarkable.

科学家研究了一位117岁西班牙妇女的细胞,发现了一些真正非凡的现象。

Her cells show signs of both extreme aging and extreme youth at the same time.

她的细胞同时展现出极度衰老和极度年轻的迹象。

Wait, how can someone be old and young at the same time?

等等,一个人怎么可能在同一时间既衰老又年轻呢?

Is she a real -life Benjamin Button?

她是现实生活中的本杰明·巴顿吗?

In a biological sense, yes.

从生物学意义上来说,是的。

While some of her tissues show normal signs of being over a century old, her immune cells and

虽然她的一些组织表现出超过一个世纪的正常老化迹象,但她的免疫细胞和

certain genetic markers look like those of a person decades younger.

某些基因标记看起来就像年轻几十岁的人一样。

Scientists believe her calm environment, strong social connections, and lack of major stress helped

科学家认为,平静的环境、强大的社交联系以及缺乏重大压力有助于

protect her cells from breaking down.

保护她的细胞免于衰竭崩溃。

That is beautiful.

那真是太美好了。

It shows that aging is not just a one -way street.

这表明衰老不仅仅是一条单行道。

We can keep parts of our bodies biologically young by staying calm, happy, and connected. Absolutely.

通过保持平静、快乐和与人联系,我们可以让身体的部分器官在生物学上保持年轻。确实如此。

A wonderful lesson on how to live a long, happy life.

关于如何过上长寿、快乐生活的一个绝佳启示。

And that brings us to the end of our news stories today.

这带我们来到了今天新闻报道的尾声。

But before we sign off, it is time for our daily quick knowledge quiz.

在签退结束之前,又是我们每日快速知识测验的时间了。

Grace, are you ready to test our listeners?

格蕾丝,你准备好测试我们的听众了吗?

I am.

我准备好了。

Here is today's question.

这是今天的问题。

What is the medical term for the bad cholesterol we discussed in our first story?

我们在第一个故事中讨论的坏胆固醇的医学术语是什么?

And what was the simple kitchen metaphor we used to explain how the new gene editing treatment works?

我们用来解释新基因编辑疗法如何运作的简单厨房隐喻是什么?

We will give our listeners a few seconds to think. Ready?

我们会给听众几秒钟时间思考。准备好了吗?

The term is LDL cholesterol.

这个术语是低密度脂蛋白胆固醇(LDL cholesterol)。

And the metaphor was a smart, white -out pen crossing out a bad, greasy recipe in a master cookbook

那个隐喻就像一支聪明的涂改液笔,划掉了主食谱中一份不好的、油腻的配方

so the kitchen stops making it.

这样厨房就会停止制作它。

Excellent job, Ethan.

做得出色,伊森。

You nailed it.

你完美搞定了它。

Now, for our open, thought -provoking question for today's Talkcast community.

现在,是今天 Talkcast 社区开放且发人深省的问题。

Since experts are doubting the benefits of dietary supplements, what is your favorite healthy food

鉴于专家们对膳食补充剂的好处表示怀疑,你最喜欢的健康食品是什么

or daily habit that you rely on to keep your mind and body feeling young?

或者是你依赖用来保持身心年轻的日常习惯是什么?

Please share your answers in the comments section below or read what other listeners have written.

请在下面的评论区分享你的答案,或者阅读其他听众的留言。

It is a fantastic, friendly space to practice your English writing and connect with other learners

这是一个极好的、友好的空间,可以练习你的英语写作,并与其他学习者交流

from around the world.

来自全世界。

Yes, we love reading your responses.

是的,我们非常喜欢阅读大家的回复。

And a quick reminder for all our dedicated English learners.

给所有专心的英语学习者一个快速提醒。

You can find the complete English transcript and audio of today's episode on our official website at

您可以在我们的官方网站上找到今天节目的完整英语逐字稿和音频

www .talkcast .top, as well as on our official WeChat public account, Talkcast.

网址是 www.talkcast.top,以及我们的官方微信公众号 Talkcast。

It is a perfect tool for reviewing vocabulary, studying the text, or checking the grammar.

这是复习词汇、研读文本或检查语法的完美工具。

Thank you all so much for your warm feedback, your amazing comments, and your continuous support.

非常感谢大家的温情反馈、精彩留言和持续的支持。

Don't forget to subscribe to Talkcast and share this podcast with your friends and family who are

不要忘记订阅 Talkcast,并将本播客分享给您身边正在

learning English.

学习英语的朋友和家人。

Have a wonderfully active, healthy, and happy day ahead.

愿你度过无比充实、健康、快乐的一天。

Wait for your coffee to cool, take a brisk walk, and keep learning.

等咖啡凉一会儿,去轻快地散散步,继续保持学习。

Goodbye, everyone.

再见,大家。

Stay healthy and stay curious. you

保持健康,保持好奇。

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